Mapping molecular pathways for improved antibodies against the HIV-1 fusion peptide, which is a key vaccine and drug target.
Understanding potent immunity against HIV-1
Mutational Fitness Landscapes of a Broadly Neutralizing Fusion Peptide-Directed Antibody Reveal Multiple Pathways to Improve HIV-1 Neutralization
Bharat Madan*, Baoshan Zhang*, Kai Xu, Jacy Wolfe, Ahmed Fahad, Cara W. Chao, Gwo-Yu Chuang, Hui Geng, Rui Kong, Mark K. Louder, Sijy O’Dell, Reda Rawi, Rajanu Fnu, Tongqing Zhou, Thuy-Duong Nguyen, Arne Schon, Zizhang Sheng, Bob Lin, Nicole A. Doria-Rose, Lawrence Shapiro, Peter D. Kwong, Brandon J. DeKosky
Mapping monoclonal anti-SARS-CoV-2 antibody repertoires against diverse coronavirus antigens
Matheus Oliveira de Souza*, Bharat Madan*, I-Ting Teng, Aric Huang, Lihong Liu, Ahmed S. Fahad, Sheila N. Lopez-Acevedo, Xiaoli Pan, Mallika Sastry, Matias Gutierrez-Gonzalez, Michael T. Yin, Tongqing Zhou, David D. Ho, Peter D. Kwong, Brandon J. DeKosky.
Strategies to screen anti-AQP4 antibodies from yeast surface display libraries
Aric Huang, Wei Jin, Ahmed S. Fahad, Brooklyn K. Mussman, Grazia Paola Nicchia, Bharat Madan, Matheus Oliveira De Souza, J. Daniel Griffin, Jeffrey L. Bennett, Antonio Frigeri, Cory J. Berkland, Brandon J. DeKosky.
Molecular Probes of Spike and Subdomains for SARS-CoV-2 Variants
I-Ting Teng, Alexandra F. Nazzari, Misook Choe, Tracy Liu, Matheus Oliveira de Souza, Yuliya Petrova, Yaroslav Tsybovsky, Baoshan Zhang, Mykhaylo Artamonov, Bharat Madan, Aric Huang, Sheila N. Lopez Acevedo, Xiaoli Pan, Tracy J. Ruckwardt, Shuishu Wang, Brandon J. DeKosky, John R. Mascola, John Misasi, Nancy J. Sullivan, Tongqing Zhou, Peter D. Kwong.
Immortalization and Functional Screening of Natively Paired Human T Cell Receptor Repertoires
Ahmed S. Fahad, Cheng Yu Chung, Sheila N. Lopez Acevedo, Nicoleen Boyle, Bharat Madan, Matias F. Gutiérrez-González, Rodrigo Matus-Nicodemos, Amy D. Laflin, Rukmini R. Ladi, John Zhou, Shauna Moore, Jacy Wolfe, Daniel C. Douek, Sian Llewellyn-Lacey, Henry H. Balfour Jr., David A. Price, Brandon J. DeKosky.
Human antibody immune responses are personalized by selective removal of MHC-II peptide epitopes
Matias Gutiérrez-González, Ahmed S. Fahad, Matt Ardito, Padma Nanaware, Erica Normandin, Bharat Madan, Joseph Tivin, Emily Coates, Amy R. Henry, Farida Laboune, Barney S. Graham, Daniel C. Douek, Julie E. Ledgerwood, John R. Mascola, William D. Martin, Lawrence J. Stern, Annie S. de Groot, Brandon J. DeKosky